经济学人2016年3月26日A jab in time

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Vaccination
A jab in time
Some Western countries have lower vaccination rates than poor parts of
Africa. Anti-vaxxers are not the main culprits

Mar 26th 2016 | From the print edition

ERADICATING a disease is the sort of aim that rich countries come up with, and
poor ones struggle to reach. But for some diseases, the pattern is reversed. These
are the ailments for which vaccinations exist. Many poor countries run highly
effective vaccination programmes. But as memories of the toll from infectious
diseases fades across the rich world, in some places they are making a comeback.
The World Health Organisation (WHO) reckons that vaccines save 2.5m lives a
year. Smallpox was eradicated in 1980 with the help of a vaccine; polio should
soon follow. In both cases, rich countries led the way. The new pattern looks very
different.

The trend is most evident for measles, which is highly contagious. At least 95% of
people must be vaccinated to stop its spread (a threshold known as “herd
immunity”). Although usually mild, it can lead to pneumonia and cause brain
damage or blindness. The countries with the lowest vaccination rates are all very
poor, but many developing countries run excellent programmes (see chart).
Eritrea, Rwanda and Sri Lanka manage to vaccinate nearly everyone. By contrast



several rich countries, including America, Britain, France and Italy, are below
herd immunity.
Last year Europe missed the deadline it had set itself in 2010 to eradicate
measles, and had almost 4,000 cases. America was declared measles-free in 2000;
in 2014 it had hundreds of cases across 27 states and last year saw its first death
from the disease in more than a decade. The trends for other
vaccine-preventable diseases, such as rubella, which can cause congenital
disabilities if a pregnant woman catches it, are alarming, too.
This sorry state of affairs is often blamed on hardline “anti-vaxxers”, parents who
refuse all vaccines for their children. They are a motley lot. The Amish in America
spurn modern medicine, along with almost everything else invented since the
17th century. Some vegans object to the use of animal- derived products in
vaccines’ manufacture. The Protestant Dutch Reformed Church thinks vaccines
thwart divine will. Anthroposophy, founded in the 19th century by Rudolf
Steiner, an Austrian mystic-cum-philosopher, preaches that diseases strengthen
children’s physical and mental development.





INTERACTIVE: Explore vaccination coverage and measles cases worldwide from
1980 to 2014

In most countries such refuseniks are only 2-3% of parents. But because they
tend to live in clusters, they can be the source of outbreaks. A bigger problem,
though, is the growing number of parents who delay vaccination, or pick and
choose jabs. Studies from America, Australia and Europe suggest that about a
quarter of parents fall into this group, generally because they think that the
standard vaccination schedule, which protects against around a dozen diseases,
“overloads” children’s immune systems, or that particular vaccines are unsafe.
Some believe vaccines interfere with “natural immunity”. Many were shaken by a
claim, later debunked, that there was a link between autism and the MMR
vaccine, which protects against measles, mumps and rubella.
In America, some poor children miss out on vaccines despite a federal
programme to provide the jabs free, since they have no regular relationship with
a family doctor. Some outbreaks in eastern Europe have started in communities
of Roma (gypsies). Members of this poor and ostracised minority are shunned by
health workers and often go unvaccinated.
Several governments are trying to raise vaccination rates by making life harder
for parents who do not vaccinate their children. A measles outbreak last year
that started with an unvaccinated child visiting Disneyland and spread from
there to seven states prompted California to make a full vaccination record a
condition of entry to state schools. The previous year, in a quarter of schools too
few children had been vaccinated against measles to confer herd immunity. A
dozen other states are considering similar bills. After a toddler died from
measles last year, Germany recently started to oblige parents who do not wish



their children to be vaccinated to discuss the decision with a doctor before they
can enroll a child in nursery. Australia’s new “no jabs, no pay” law withdraws
child benefits from parents who do not vaccinate, unless they have sound
medical reasons.
Persuasion, a fine art
There is, however, surprisingly little evidence that tough laws make a big
difference to vaccination rates. European countries that are similar in most
respects (such as the Nordics) may have similar rates for jabs that are mandatory
in one country but not in another—or very different rates despite having the
same rules. Rates in some American states where parents can easily opt out are
as high as in West Virginia and Mississippi, which have long allowed only
medical exemptions.
And strict rules may even harden anti-vaccination attitudes. Australia had
previously made exemption conditional on speaking to a doctor or nurse about
the benefits of vaccines. The new rules mean fewer chances to change parents’
minds. Research suggests that making it harder to avoid the most important
vaccines may make it more likely that people who strongly oppose vaccination in
general shun optional ones, says Cornelia Betsch of the University of Erfurt.
More important, say public-health experts, is to boost confidence in the safety of
vaccines and trust in the authorities that recommend them—both badly
damaged in many European countries by pastpublic-health mis-steps, such as a
scandal with contaminated blood supply in France from the late 1990s. The best
way to handle a vaccine scare is to express empathy and promptly share the
results from investigations of alleged adverse reactions, says Heidi Larson of the
London School of Hygiene and Tropical Medicine. British authorities’ dismissive
response to the MMR scare failed to reassure worried parents.
One promising new approach is to keep track of the vaccine myths circulating in
cyberspace and rebut each one as it appears. This requires tracking information
from search engines and following anti-vaccination websites and parents’ forums.
On one such forum, worriers say they have scoured government and
vaccine-manufacturer websites but feel overwhelmed by information that they
regard as inconclusive or contradictory. One mother seeks advice on how to get
around California’s “fascist” new rule. Another casts doubt on a study on severe
allergic reactions to vaccines: 33 cases from 25m jabs, she says, seems “fishily
low”.
Some countries are starting information campaigns that treat such concerns with
respect. A parents’ organisation in Bulgaria launched one recently, under the



auspices of the ministry of health and the national association of paediatricians.
Its website is jargon-free and easier to navigate than unwieldy official hubs.
France is launching a national dialogue on vaccines this spring, with a website
where citizens can swap gripes, worries and advice.
Although vaccine- hesitant parents often search for answers on the internet, their
most trusted sources are doctors and nurses. The WHO recently developed
guidelines to help health workers figure out, through a questionnaire, which type
of worrier a parent is—and how to alleviate specific concerns. But recent
research from several European countries shows that many doctors and nurses
are also hesitant about vaccines, for much the same reasons as their patients. In a
survey conducted in 2014, 16-43% of French family doctors said they never or
only sometimes recommended some of the standard vaccines.
An additional problem is that many adults were not immunised as children and
have not caught up since. In the 1970s and 1980s, when the measles vaccine was
new, many children did not receive it, or got just one shot, which is now known
not to be reliable in conferring immunity. Some countries offer free catch-up jabs
to some adults when outbreaks flare up—usually parents with small children
and health workers in affected areas.
But such efforts have, on the whole, been too little, too late. The return of easily
preventable diseases that had all but disappeared is a shame. A bigger shame
would be for governments to continue blaming it all on ignorant parents.

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